Does autonomic dysfunction play a role in atopic dermatitis?


Cicek D., Kandi B., Berilgen M. S. , Bulut S., Tekatas A., Dertlioglu S. B. , ...More

BRITISH JOURNAL OF DERMATOLOGY, vol.159, no.4, pp.834-838, 2008 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 159 Issue: 4
  • Publication Date: 2008
  • Doi Number: 10.1111/j.1365-2133.2008.08756.x
  • Title of Journal : BRITISH JOURNAL OF DERMATOLOGY
  • Page Numbers: pp.834-838

Abstract

Background Atopic dermatitis (AD) is a chronic dermatitis characterized by intense itching and excessive skin dryness. The factor most commonly blamed for the pathogenesis of skin dryness in the disease is impaired barrier function of the stratum corneum. However, there are findings indicating that the autonomic nervous system, and the sympathetic nervous system in particular, is affected negatively in AD, and thus, autonomic dysfunction can be an important factor leading to skin dryness.