Infliximab Modulates Cisplatin-Induced Hepatotoxicity in Rats


Cure M. C. , Cure E., Kalkan Y., Kirbas A., Tumkaya L. , Yilmaz A., ...Daha Fazla

BALKAN MEDICAL JOURNAL, cilt.33, ss.504-511, 2016 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 33 Konu: 5
  • Basım Tarihi: 2016
  • Doi Numarası: 10.5152/balkanmedj.2016.150576
  • Dergi Adı: BALKAN MEDICAL JOURNAL
  • Sayfa Sayıları: ss.504-511

Özet

Background: Cisplatin (Cis) is one of the most commonly used antineoplastic drugs. It is used as chemotherapy for many solid organ malignancies such as brain, neck, male and female urogenital, vesical and pulmonary cancers. Infliximab blocks tumor necrosis factor alpha (TNF-alpha). Several studies have reported that infliximab ameliorates cell damage by reducing cytokine levels.