Plica Neuropatica (Plica polonica) is a common but rarely reported scalp disease. In a localized area, the hair of the scalp is irregularly twisted and irreversibly entangled in the form of a natural hair bun. Mental disorders are a risk factor for plica formation. In this study, we will discuss the case of plica neuropatica in a 46-year-old schizophrenic patient with decreased self-care and predominantly negative symptoms with social withdrawal. Early diagnosis and treatment of the underlying psychiatric disease will prevent the formation of plica.