Microwave-assisted synthesis and antifungal activity of some new 1H-1,2,4-triazole derivatives


KAHVECI B., ÖZİL M. , MENTEŞE E. , Bekircan O., Buruk K.

RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, vol.44, no.12, pp.1816-1820, 2008 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 44 Issue: 12
  • Publication Date: 2008
  • Doi Number: 10.1134/s1070428008120178
  • Title of Journal : RUSSIAN JOURNAL OF ORGANIC CHEMISTRY
  • Page Numbers: pp.1816-1820

Abstract

A number of 3-aryl-4-arylmethylideneamino-4,5-dihydro-1H-1,2,4-triazol-5-ones were synthesized by reaction of the corresponding aromatic aldehydes with 4-amino-3-aryl-1H-1,2,4-triazol-5-ones in anhydrous ethanol under microwave irradiation. The newly synthesized 1H-1,2,4-triazole derivatives were tested for antimicrobial activity. They showed no antibacterial activity but slight mycostatic activity against some Candida species.