Microwave-Assisted Synthesis of Benzoxazole Derivatives


ÖZİL M. , MENTEŞE E.

Current Microwave Chemistry, vol.7, no.3, pp.183-195, 2020 (Journal Indexed in ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 7 Issue: 3
  • Publication Date: 2020
  • Doi Number: 10.2174/2213335607999200518094114
  • Title of Journal : Current Microwave Chemistry
  • Page Numbers: pp.183-195
  • Keywords: Benzoxazoles, microwave, synthesis, heterocyclic, green chemistry, solvent free, catalyst free, bioactive, ONE-POT SYNTHESIS, EFFICIENT SYNTHESIS, 2-SUBSTITUTED BENZOXAZOLES, POLYPHOSPHORIC ACID, MOLECULAR DOCKING, ORGANIC-SYNTHESIS, CARBOXYLIC-ACIDS, BENZIMIDAZOLES, BENZOTHIAZOLE, ANTICANCER

Abstract

Background: Benzoxazole, containing a 1,3-oxazole system fused with a benzene ring, has a profound effect on medicinal chemistry research owing to its important pharmacological activities. On the other hand, the benzoxazole derivative has exhibited important properties in material science. Especially in recent years, microwave-assisted synthesis is a technique that can be used to increase diversity and quick research in modern chemistry. The utilization of microwave irradiation is beneficial for the synthesis of benzoxazole in recent years. In this focused review, we provide a meta analysis of studies on benzoxazole in different reaction conditions, catalysts, and starting materials by microwave technique so far, which is different from conventional heating.