Beneficial effects of Ebselen on corrosive esophageal burns of rats

Ocakci A., Coskun O., Tumkaya L., Kanter M., Gurel A., Hosnuter M., ...More

INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY, vol.70, no.1, pp.45-52, 2006 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 70 Issue: 1
  • Publication Date: 2006
  • Doi Number: 10.1016/j.ijporl.2005.05.018
  • Journal Name: INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.45-52
  • Keywords: Ebselen, stricture, caustic burn, corrosive esophagitis, fibrosis, lipid peroxidation, antioxidant enzymes, rat, ALKALI BURNS, INHIBITION, INJURY, SUPEROXIDE, STRICTURES, MANAGEMENT, COLLAGEN, CHILDREN, THERAPY, PZ-51
  • Recep Tayyip Erdoğan University Affiliated: No

Abstract

Aim: This study was evaluated to investigate the efficacy of Ebselen, which is an organoselenium compound and glutathione peroxidase mimic, on the prevention of stricture development after esophageal caustic injuries in the rat.