Effects of early administration of dexamethasone, N-acetylcysteine and aprotinin on inflammatory and oxidant-antioxidant status after lung contusion in rats


TÜRÜT H. , Ciralik H., Kilinc M., Ozbag D., Imrek S. S.

INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED, cilt.40, sa.5, ss.521-527, 2009 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 40 Konu: 5
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1016/j.injury.2008.05.001
  • Dergi Adı: INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
  • Sayfa Sayıları: ss.521-527

Özet

Introduction: This experimental setting was undertaken to elucidate and confirm the role of inflammatory and oxidant-antioxidant mechanisms on blunt injury induced moderate pulmonary contusion (PC). We intended to determine the effects of dexamethasone (DXM), N-acetylcysteine (NAC) and aprotinin (APR) in terms of their ability to diminish the consequences of acute lung injury due to PC.