Evaluation of Microsatellite Instability in Colorectal Adenomas and Carcinomas by Immunohistochemistry and a Comparison of Histopathological Features


YILMAZ R., Bedir R. , Akdogan R. A. , PERGEL A.

EUROPEAN JOURNAL OF THERAPEUTICS, cilt.25, ss.28-38, 2019 (ESCI İndekslerine Giren Dergi) identifier

  • Cilt numarası: 25 Konu: 1
  • Basım Tarihi: 2019
  • Doi Numarası: 10.5152/eurjther.2018.582
  • Dergi Adı: EUROPEAN JOURNAL OF THERAPEUTICS
  • Sayfa Sayıları: ss.28-38

Özet

Objective: Approximately 15% of sporadic colorectal carcinomas (CRCs) develop along the microsatellite instability (MSI) pathway. In this study, we compared the MLH1, MSH2, Ki-67, and p53 immunostaining properties with histopathological features of colorectal adenomas and CRCs.