Oxidative status and prolidase activities in generalized anxiety disorder

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Ercan A. C., Bahceci B., Polat S., Cenker O. C., Bahceci I., Koroglu A., ...More

ASIAN JOURNAL OF PSYCHIATRY, vol.25, pp.118-122, 2017 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 25
• Publication Date: 2017
• Doi Number: 10.1016/j.ajp.2016.10.008
• Journal Name: ASIAN JOURNAL OF PSYCHIATRY
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.118-122
• Keywords: Generalized anxiety disorder, Oxidative stress, Prolidase, Total oxidant status, Total anxiety disorder, OBSESSIVE-COMPULSIVE DISORDER, ANTIOXIDANT ENZYME-ACTIVITIES, LIPID-PEROXIDATION, BIPOLAR DISORDER, MALONDIALDEHYDE LEVELS, PANIC DISORDER, FREE-RADICALS, NITRIC-OXIDE, IN-VIVO, STRESS
• Recep Tayyip Erdoğan University Affiliated: Yes

Abstract

Objective: Prolidase (Pro), an intracellular enzyme necessary for collagen turnover, matrix remodelling and cell growth has been shown to be related to Oxidative Stress (OS). To our knowledge, serum Pro activity in generalized anxiety disorder (GAD) has not been documented yet. In this study, we aimed to evaluate OS and its relation with Pro activity in patients diagnosed with GAD.