Mild hypoglycaemic attacks induced by sulphonylureas related to CYP2C9, CYP2C19 and CYP2C8 polymorphisms in routine clinical setting

Gokalp, Osman; GUNES, Arzu; Cam, Hakan; Cure, ERKAN; Aydin, Osman; Tamer, Mehmet; Scordo, Maria; Dahl, Marja-Liisa

doi:10.1007/s00228-011-1078-4

Mild hypoglycaemic attacks induced by sulphonylureas related to CYP2C9, CYP2C19 and CYP2C8 polymorphisms in routine clinical setting

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Gokalp O., GUNES A., Cam H., Cure E., Aydin O., Tamer M. N., ...More

EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, vol.67, no.12, pp.1223-1229, 2011 (SCI-Expanded)

Publication Type: Article / Article
Volume: 67 Issue: 12
Publication Date: 2011
Doi Number: 10.1007/s00228-011-1078-4
Journal Name: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.1223-1229
Recep Tayyip Erdoğan University Affiliated: No

Abstract

To evaluate the impact of polymorphisms in the cytochrome P450 (CYP) 2C9, 2C19 and 2C8 genes on the risk of mild hypoglycaemic attacks in patients treated with sulphonylureas.