II. BASKENT INTERNATIONAL CONFERENCE ON MULTIDISCIPLINARY STUDIES, Ankara, Türkiye, 24 - 25 Şubat 2022, ss.10-11
ABSTRACT
Pilonidal
disease is a benign disease with chronic recurrent inflammation frequently seen
in men. It is most commonly found in the sacrococcygeal region. It can also be
seen in many places such as the umbilicus and axilla.
Malignant
degeneration is a rare complication mainly observed in chronic, recurrent and
untreated primary pilonidal disease and is associated with poor prognosis.
Malignant degeneration is extremely rare and occurs in about 0.1% of cases. It
is usually diagnosed incidentally in the excision materials. The most common
type of malignancy is squamous cell carcinoma (90%). Basal cell carcinoma and
adenocarcinoma are less common.
Wide
excision with tumor-free margins is the preferred treatment. The efficacy of
radiotherapy and chemotherapy is limited.
Our
cases were two male patients aged 50 and 52 years. In both patients, the
disease course was more than approximately 15 years. Both patients had fistula
openings in the intergluteal sulcus and gluteal region. Peripheral LAP was not
palpated. Both patients were repaired using the wide excision and flap method.
The pathology results of both patients revealed squamous cell carcinoma. One of
the patients who was referred to the postoperative oncology clinic could not be
followed up because he went out of the province. The other patient is being
followed up by oncology after surgical resection and did not receive adjuvant
treatment.
In
conclusion, pilonidal sinus is a benign disease and its malignancy rate is
quite low. However, it should be kept in mind that malignancy may develop after
recurrent episodes of inflammation that have not received long-term treatment.
Especially in the presence of widespread sinus openings and inflammation around
its current location, malignancy should be considered. The mainstay of
treatment is wide surgical excision. The efficacy of adjuvant treatments is
limited. Although abscess drainage and antibiotic therapy can be used in its
treatment, total excision should be performed due to the risk of malignancy.
Key
words: pilonidal sinus, malignant degeneration, SCC