Prognostic significance of NGAL in early stage chronic kidney disease

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Basturk T., Sari O., Koc Y., Eren N., Isleem M., Kara E., ...More

MINERVA UROLOGICA E NEFROLOGICA, vol.69, no.3, pp.307-312, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 69 Issue: 3
  • Publication Date: 2017
  • Doi Number: 10.23736/s0393-2249.16.02770-3
  • Journal Name: MINERVA UROLOGICA E NEFROLOGICA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.307-312
  • Keywords: Lipocalin-2, Biomarkers, Renal insufficiency, chronic, GELATINASE-ASSOCIATED LIPOCALIN, RENAL-FUNCTION, CYSTATIN C, SERUM, MARKER, BIOMARKERS, CREATININE
  • Recep Tayyip Erdoğan University Affiliated: Yes

Abstract

BACKGROUND: Neutrophilgelatinase-associated lipocalin (NGAL) has been proven to be a useful biomarker for early detection of acute kidney injury, but it is not known whether adding NGAL measurements to conventional risk factors will improve the risk assessment in the setting of chronic kidney disease (CKD). The aim of the present study was to examine the correlation of NGAL with early stage renal impairment in CKD and to evaluate its prognostic value in these subjects.