A Rapid Protocol for the Synthesis of <i>N</i>-[2-(alkyl/aryl)-4-phenyl-1<i>H</i>-imidazol-1-yl] benzamides <i>via</i> Microwave Technique

YILMAZ F., MENTEŞE E.

CURRENT MICROWAVE CHEMISTRY, cilt.1, sa.1, ss.47-51, 2014 (ESCI) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 1 Sayı: 1
  • Basım Tarihi: 2014
  • Doi Numarası: 10.2174/2213335601999140221111915
  • Dergi Adı: CURRENT MICROWAVE CHEMISTRY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI)
  • Sayfa Sayıları: ss.47-51
  • Recep Tayyip Erdoğan Üniversitesi Adresli: Evet

Özet

Benzohydrazides (2a-g) were synthesized starting from iminoester hydrochlorides and benzhydrazide. The treatment of compounds 2a-g with phenylacyl bromide derivatives gave N-[2-(alkyl/aryl)-4-phenyl-1H-imidazol-1-yl] benzamides. The synthetic protocol was performed under microwave irradiation and the lowest quantity of the solvent was used to obtain the best green protocol. This method has been found to be more efficient than others in terms of green chemistry.