Relationship of osteoprotegerin to pulse wave velocity and carotid intima-media thickness in rheumatoid arthritis patients


Beyazal M., Erdogan T., DEVRIMSEL G., TURKYILMAZ A. K. , CURE M. C. , Beyazal M., ...More

ZEITSCHRIFT FUR RHEUMATOLOGIE, vol.75, no.7, pp.723-728, 2016 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 75 Issue: 7
  • Publication Date: 2016
  • Doi Number: 10.1007/s00393-015-1675-1
  • Journal Name: ZEITSCHRIFT FUR RHEUMATOLOGIE
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.723-728
  • Keywords: Cardiovascular diseases, Ultrasonography, Atherosclerosis, Inflammation, Risk factors, CARDIOVASCULAR RISK-FACTORS, ARTERIAL STIFFNESS, ENDOTHELIAL DYSFUNCTION, DISEASE-ACTIVITY, ATHEROSCLEROSIS, INFLAMMATION, WOMEN, PREDICTOR, MORBIDITY, MORTALITY

Abstract

Osteoprotegerin (OPG) is considered an important biomarker in cardiovascular (CV) disease. CV disease is the most common cause of mortality in patients with rheumatoid arthritis (RA), a consequence of accelerated atherosclerosis. The present study aimed to evaluate the relationship of serum OPG levels to arterial stiffness, carotid intima-media thickness (CIMT), and clinical and laboratory indices in RA patients.