The relationship of plasma catestatin concentrations with metabolic and vascular parameters in untreated hypertensive patients: Influence on high-density lipoprotein cholesterol

Durakoglugil M. E., AYAZ T., KOCAMAN S. A., KIRBAS A., DURAKOGLUGIL T., ERDOGAN T., ...More

ANATOLIAN JOURNAL OF CARDIOLOGY, vol.15, no.7, pp.577-585, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 15 Issue: 7
  • Publication Date: 2015
  • Doi Number: 10.5152/akd.2014.5536
  • Journal Name: ANATOLIAN JOURNAL OF CARDIOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.577-585
  • Keywords: catestatin, hypertension, high-density lipoprotein cholesterol, sympatho-adrenal flow, low HDL-C, INHIBITORY PEPTIDE CATESTATIN, CHROMOGRANIN-A FRAGMENT, CATECHOLAMINE RELEASE, IN-VIVO, A(352-372), HUMANS, SYSTEM, ARTERY, RISK
  • Recep Tayyip Erdoğan University Affiliated: Yes

Abstract

Objective: Catestatin has several cardiovascular actions, in addition to diminished sympatho-adrenal flow. Decreased plasma catestatin levels may reflect a predisposition for the development of hypertension and metabolic disorders. We planned to investigate the possible roles of catestatin in untreated hypertensive patients. As a secondary objective, we compared catestatin concentrations of healthy subjects with those of hypertensive patients in order to understand whether catestatin is increased reactively or diminished at onset.