The relationship of plasma catestatin concentrations with metabolic and vascular parameters in untreated hypertensive patients: Influence on high-density lipoprotein cholesterol
ANATOLIAN JOURNAL OF CARDIOLOGY, cilt.15, sa.7, ss.577-585, 2015 (SCI-Expanded, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 15 Sayı: 7
- Basım Tarihi: 2015
- Doi Numarası: 10.5152/akd.2014.5536
- Dergi Adı: ANATOLIAN JOURNAL OF CARDIOLOGY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.577-585
- Anahtar Kelimeler: catestatin, hypertension, high-density lipoprotein cholesterol, sympatho-adrenal flow, low HDL-C, INHIBITORY PEPTIDE CATESTATIN, CHROMOGRANIN-A FRAGMENT, CATECHOLAMINE RELEASE, IN-VIVO, A(352-372), HUMANS, SYSTEM, ARTERY, RISK
- Recep Tayyip Erdoğan Üniversitesi Adresli: Evet
Özet
Objective: Catestatin has several cardiovascular actions, in addition to diminished sympatho-adrenal flow. Decreased plasma catestatin levels may reflect a predisposition for the development of hypertension and metabolic disorders. We planned to investigate the possible roles of catestatin in untreated hypertensive patients. As a secondary objective, we compared catestatin concentrations of healthy subjects with those of hypertensive patients in order to understand whether catestatin is increased reactively or diminished at onset.