Aortic valve sclerosis is a high predictive marker of systemic endothelial dysfunction in hypertensive patients

Erdoğan T., Çetin M., KOCAMAN S. A., Durakoglugil M. E., ERGUL E., CANGA A.

HERZ, vol.38, no.8, pp.915-921, 2013 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 38 Issue: 8
  • Publication Date: 2013
  • Doi Number: 10.1007/s00059-013-3763-9
  • Journal Name: HERZ
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.915-921
  • Keywords: Aortic sclerosis, Endothelial dysfunction, Carotid intima-media thickness, Epicardial adipose tissue, Arterial stiffness, Positive predictive value, Hypertension, INTIMA-MEDIA THICKNESS, EPICARDIAL ADIPOSE-TISSUE, LEFT-VENTRICULAR MASS, CARDIOVASCULAR MORTALITY, EMERGING ROLE, TASK-FORCE, ALL-CAUSE, STENOSIS, DISEASE, PROGRESSION
  • Recep Tayyip Erdoğan University Affiliated: Yes


Background. Aortic valve sclerosis (AVS) is closely related to hypertension and is an important predictor of coronary artery disease as well as cardiovascular morbidity and mortality. However, the mechanisms causing AVS have not yet been clarified. Therefore, we planned to investigate the influence of atherosclerosis-related risk factors including C-reactive protein (CRP), epicardial adipose tissue (EAT), carotid intima-media thickness (CIMT), pulse wave velocity (PWV), left ventricular hypertrophy, and the conventional risk parameters as well as endothelial dysfunction in untreated hypertensive patients.