Aortic valve sclerosis is a high predictive marker of systemic endothelial dysfunction in hypertensive patients

Erdoğan T. , Çetin M. , KOCAMAN S. A. , Durakoglugil M. E. , ERGUL E., CANGA A.

HERZ, cilt.38, sa.8, ss.915-921, 2013 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 38 Konu: 8
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1007/s00059-013-3763-9
  • Dergi Adı: HERZ
  • Sayfa Sayıları: ss.915-921


Background. Aortic valve sclerosis (AVS) is closely related to hypertension and is an important predictor of coronary artery disease as well as cardiovascular morbidity and mortality. However, the mechanisms causing AVS have not yet been clarified. Therefore, we planned to investigate the influence of atherosclerosis-related risk factors including C-reactive protein (CRP), epicardial adipose tissue (EAT), carotid intima-media thickness (CIMT), pulse wave velocity (PWV), left ventricular hypertrophy, and the conventional risk parameters as well as endothelial dysfunction in untreated hypertensive patients.