European Journal of Oncology, vol.20, no.2, pp.109-113, 2015 (SCI-Expanded)
Summary. Primary malignant lymphoma of the trachea is rare and its underlying mechanism remains unknown.
Primary tracheal tumors are also very rare causes of airway obstructions. This case report features
a 60 year-old woman who presented with the complaint of dyspnea. A mass narrowing the tracheal lumen
posteriorly in the subglottic area and mediastinal lymphadenopathy was detected by computed tomography
scan and a rijit bronchoscopy was performed. This showed polypoid, variable-sized, irregular nodules causing
narrowing of the tracheal lumen over a 3 cm segment in the middle part of the trachea and a mass protruding
into the tracheal lumen from the posterior part of the proximal trachea. Multiple biopsy was carried out from
the nodules and the airway obstruction was treated with Argon Plasma Coagulation (APC). After removal
of the debris, tracheal lumen patency was obtained. The histopathology examination revealed a small lymphocytic
primary non-Hodgkin’s lymphoma of the trachea. To our knowledge, this is the first case of small
lymphocytic primary tracheal lymphoma in the literature.