IRANIAN JOURNAL OF KIDNEY DISEASES, cilt.9, sa.3, ss.221-229, 2015 (SCI-Expanded)
Introduction. Methotrexate, an antagonist of folic acid used in the treatment of many cancers and inflammatory diseases, is associated with side effects that limit its usage. Infliximab has been reported to have a protective effect against nephrotoxicity induced by some drugs and ischemic reperfusion. We aimed to investigate whether infliximab has a protective effect against methotrexate-induced nephrotoxicity.