Advances in Bioscience and Clinical Medicine, vol.3, no.3, pp.19-23, 2014 (Refereed Journals of Other Institutions)
Background: The importance of rapid and accurate cytopathological diagnosis in bronchial
cancers is increasing due to advances in treatment modalities.
Aims: We evaluated the diagnostic methods and cytologic subtypes of bronchial cancers to
determine the diagnostic reliability of different bronchoscopic techniques.
Material and methods: Retrospective data were obtained from the hospital files and
pathological specimens of the patients with diagnosis of primary lung cancer from a period of
36 months. Cytological tumor typing was determined using histopathology of bronchoscopic
forceps biopsy (FB), bronchial-bronchoalveolar lavage (BL), bronchial brushing (BB),
transbronchial fine-needle biopsy. Computed tomography or ultrasonography guided
transthoracic biopsy and surgical biopsies were used where the other interventional methods
were inadequate for diagnosis.
Results: A total of 124 patients were diagnosed during study period. 119 (96%) of them were
male. The median age was 68, ranging between 36 and 88 years. Histopathologic subtypes
were determined as non-small cell carcinoma (NSCC) in 104 (83.9%), squamous cell carcinoma
in 64 (51.6%), adenocarcinoma in 16 (12.9%), NSCC not otherwise specified in 24 (19.3%) and
small cell carcinoma in 20 (16.1%) patients. The combination of FB, BL and BB established the
diagnosis of bronchogenic carcinoma in most of the cases (92.6%).
Conclusions: Lung cancer is seen commonly in elderly male patients with smoking history and
squamous cell carcinoma is the most common cytologic type. High diagnostic accuracy can be
achieved by a combination of bronchoscopic FB, BB and BL procedures.
Keywords: Bronchoscopy; Lung cancer; Bronchial brushing