Bronchial Brushing Increases the Diagnostic Yield of Fiberoptic Bronchoscopy in Bronchogenic Carcinoma.

Bedir R., Kayhan S., Şehitoğlu I., Çınarka H., Gümüş A., Kurt A., ...More

Advances in Bioscience and Clinical Medicine, vol.3, no.3, pp.19-23, 2014 (Peer-Reviewed Journal)

  • Publication Type: Article / Article
  • Volume: 3 Issue: 3
  • Publication Date: 2014
  • Journal Name: Advances in Bioscience and Clinical Medicine
  • Journal Indexes: Directory of Open Access Journals
  • Page Numbers: pp.19-23
  • Recep Tayyip Erdoğan University Affiliated: Yes


Background: The importance of rapid and accurate cytopathological diagnosis in bronchial
cancers is increasing due to advances in treatment modalities.
: We evaluated the diagnostic methods and cytologic subtypes of bronchial cancers to
determine the diagnostic reliability of different bronchoscopic techniques.
Material and methods: Retrospective data were obtained from the hospital files and
pathological specimens of the patients with diagnosis of primary lung cancer from a period of
36 months. Cytological tumor typing was determined using histopathology of bronchoscopic
forceps biopsy (FB), bronchial-bronchoalveolar lavage (BL), bronchial brushing (BB),
transbronchial fine-needle biopsy. Computed tomography or ultrasonography guided
transthoracic biopsy and surgical biopsies were used where the other interventional methods
were inadequate for diagnosis.
: A total of 124 patients were diagnosed during study period. 119 (96%) of them were
male. The median age was 68, ranging between 36 and 88 years. Histopathologic subtypes
were determined as non-small cell carcinoma (NSCC) in 104 (83.9%), squamous cell carcinoma
in 64 (51.6%), adenocarcinoma in 16 (12.9%), NSCC not otherwise specified in 24 (19.3%) and
small cell carcinoma in 20 (16.1%) patients. The combination of FB, BL and BB established the
diagnosis of bronchogenic carcinoma in most of the cases (92.6%).
: Lung cancer is seen commonly in elderly male patients with smoking history and
squamous cell carcinoma is the most common cytologic type. High diagnostic accuracy can be
achieved by a combination of bronchoscopic FB, BB and BL procedures.
Keywords: Bronchoscopy; Lung cancer; Bronchial brushing