Diagnostic Value of Serum Thiobarbituric Acid Reactive Substances Levels in Pediatric Acute Appendicitis

Altuntaş G., Altuntaş M., Atak M.

Sakarya Tıp Dergisi, vol.14, no.1, pp.28-33, 2024 (Peer-Reviewed Journal)

  • Publication Type: Article / Article
  • Volume: 14 Issue: 1
  • Publication Date: 2024
  • Doi Number: 10.31832/smj.1351769
  • Journal Name: Sakarya Tıp Dergisi
  • Journal Indexes: TR DİZİN (ULAKBİM)
  • Page Numbers: pp.28-33
  • Recep Tayyip Erdoğan University Affiliated: Yes


Purpose: This study aims to show the diagnostic value of Serum Thiobarbituric Acid Reactive Substances in pediatric appendicitis.
Method: Eighty-five pediatric patients hospitalized in the pediatric surgery ward with acute appendicitis and a control group of 50 pediatric patients with unspecific abdominal pain were included in this prospective case-control study. Forty-five patients whose pathology specimens confirmed acute appendicitis made up the final appendicitis group.
Results: Patients with appendicitis had higher Serum Thiobarbituric Acid Reactive Substances (p<0.001) levels than the control group. In receiver operating characteristic analysis, areas under the curve were 0.654 for Serum Thiobarbituric Acid Reactive Substances.
Conclusion: Serum Thiobarbituric Acid Reactive Substances test of patients with appendicitis provides limited accuracy in the diagnosis of appendicitis.