The protective effects of adalimumab on intestinal injury induced with infrarenal aortic occlusion

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Pergel A., Tumkaya L., Demiral G., Colakoglu M. K., Kalcan S., Özdemir A., ...More

ULUSAL TRAVMA VE ACIL CERRAHI DERGISI-TURKISH JOURNAL OF TRAUMA & EMERGENCY SURGERY, vol.26, no.3, pp.366-372, 2020 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 26 Issue: 3
  • Publication Date: 2020
  • Doi Number: 10.14744/tjtes.2019.59607
  • Journal Name: ULUSAL TRAVMA VE ACIL CERRAHI DERGISI-TURKISH JOURNAL OF TRAUMA & EMERGENCY SURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CINAHL, EMBASE, MEDLINE, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.366-372
  • Keywords: Adalimumab, intestinal injury, ischemia, oxidative stress, rat, reperfusion, ISCHEMIA-REPERFUSION INJURY, TNF-ALPHA, RAT MODEL, ISCHEMIA/REPERFUSION, INFLIXIMAB, APOPTOSIS, DAMAGE
  • Recep Tayyip Erdoğan University Affiliated: Yes

Abstract

BACKGROUND: The present study aims to observe the effects of ischemia-reperfusion (IR) on small intestines at a molecular level and to prospectively assess the potential preventive role of adalimumab (ADA) and antioxidants.