Green-synthesized zinc and iron nanoparticles enhance basil drought tolerance via antioxidant regulation


Selvikaya I., Karataş R., Karakuş M., Yilmaz H., Demirel F., Güler E., ...Daha Fazla

BMC PLANT BIOLOGY, cilt.1, sa.1, ss.1-26, 2026 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 1 Sayı: 1
  • Basım Tarihi: 2026
  • Doi Numarası: 10.1186/s12870-026-09935-3
  • Dergi Adı: BMC PLANT BIOLOGY
  • Derginin Tarandığı İndeksler: Academic Search Ultimate (EBSCO), Natural Science Collection (ProQuest), Biological Science Database (ProQuest), Biomedical Reference Collection: Corporate Edition (EBSCO), Health Research Premium Collection (ProQuest), Scopus, Science Citation Index Expanded (SCI-EXPANDED), BIOSIS, EMBASE, MEDLINE, Directory of Open Access Journals
  • Sayfa Sayıları: ss.1-26
  • Recep Tayyip Erdoğan Üniversitesi Adresli: Evet

Özet

Abstract Background Drought is a major abiotic constraint that disrupts growth, physiology, and metabolic balance in medicinal and aromatic plants. This study examined how green-synthesized zinc (Zn) oxide and iron (Fe) oxide nanoparticles (NPs) influence drought tolerance in basil ( Ocimum basilicum L.). A factorial greenhouse experiment evaluated two irrigation regimes (100% and 50% field capacity, FC) combined with four foliar treatments: control, Zn (100 mg L⁻ 1 ), Fe (100 mg L⁻ 1 ), and Zn + Fe (50 + 50 mg L⁻ 1 ), which represent agronomically realistic and field-applicable concentrations. Nanoparticles biosynthesized using sage ( Salvia officinalis ) extract were characterized by scanning electron microscopy/energy dispersive X-ray spectroscopy (SEM/EDS). Results Under drought conditions, NP supplementation mitigated growth reductions by increasing plant height by up to 26.7%, leaf number by 30.6%, and biomass by 22.6% compared to untreated drought controls. The combined Zn + Fe treatment elicited trait-specific responses, particularly increasing phenolic and flavonoid contents by 53% and 48%, respectively, and notably enhancing catalase (CAT) and ascorbate peroxidase (APX) activities by 204% and 86% relative to drought controls. Consequently, oxidative stress markers (malondialdehyde [MDA], hydrogen peroxide [H₂O₂]) were reduced by nearly 50%. Zn primarily enhanced non-enzymatic antioxidant capacity by increasing cupric reducing antioxidant capacity [CUPRAC], ferric reducing antioxidant power [FRAP], and 2,2-diphenyl-1-picrylhydrazyl [DPPH] by 135%, 48%, and 17%, respectively, whereas Fe supported enzymatic detoxification through a 27% increase in superoxide dismutase (SOD) activation compared to drought controls. Correlation analysis showed strong associations among antioxidant capacity, pigment levels, and growth traits, and principal component analysis (PCA) distinguished Zn + Fe-treated plants within antioxidant-rich and high-biomass clusters, indicating coordinated redox regulation. Conclusions Foliar nano-micronutrition with green-synthesized Zn NPs and Fe NPs strengthened antioxidant defenses, stabilized pigments, and improved growth resilience under drought, providing physiological and biochemical evidence of nanoparticle-mediated modulation of stress responses.