Synthesis of Some New Benzimidazole Derivatives with their Antioxidant Activities

Usta A., Yilmaz F., KAPUCU G., Baltas N., Mentese E.

LETTERS IN ORGANIC CHEMISTRY, vol.12, no.4, pp.227-232, 2015 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 12 Issue: 4
  • Publication Date: 2015
  • Doi Number: 10.2174/1570178612666150203233804
  • Journal Name: LETTERS IN ORGANIC CHEMISTRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.227-232
  • Keywords: Benzimidazole, Oxadiazole, 1, 2, 4-Triazole, Salicyl group, DPPH, ABTS(center dot+), ANTIBACTERIAL ACTIVITY, KETONES, MOIETY
  • Recep Tayyip Erdoğan University Affiliated: Yes

Abstract

In this paper, some benzimidazole derivatives containing salicyl, oxadiazole, thiosemicarbazide and 1, 2, 4-triazole moieties have been synthesized and screened their antioxidant activities screened. Antioxidant activities of the synthesized compounds were tested with DPPH and ABTS(center dot+) radical cation decolorization assays. Compounds 4b, 6a, 6b, 7a and 7b showed very good scavenging activity.