Serum concentrations of human insulin-like growth factor-1 and levels of insulin-like growth factor-binding protein-5 in patients with nonalcoholic fatty liver disease: association with liver histology


Colak Y., Senates E., Ozturk O., YILMAZ Y., Zemheri E., Enc F. Y., ...More

EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, vol.24, no.3, pp.255-261, 2012 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 24 Issue: 3
  • Publication Date: 2012
  • Doi Number: 10.1097/meg.0b013e32834e8041
  • Journal Name: EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.255-261
  • Keywords: fatty liver, insulin-like growth factor-I, insulin-like growth factor binding protein-5, NECROSIS-FACTOR-ALPHA, IGF-I, HEPATOCELLULAR-CARCINOMA, HEPATOCYTE APOPTOSIS, CELLULAR SENESCENCE, PULMONARY-FIBROSIS, METABOLIC SYNDROME, SIMPLE STEATOSIS, STEATOHEPATITIS, POPULATION
  • Recep Tayyip Erdoğan University Affiliated: No

Abstract

Objective In this study, we aimed to investigate the relationship between the histological features of nonalcoholic fatty liver disease (NAFLD) and serum insulin-like growth factor-1 (IGF-1) and insulin-like growth factor-binding protein-5 (IGFBP-5) to determine the usefulness of this relationship in clinical practice.