Circulating parameters of oxidative stress and hypoxia in normal pregnancy and HELLP syndrome

MENTEŞE A., GÜVEN S., DEMİR S., Sumer A., ÖZER YAMAN S., ALVER A., ...Daha Fazla

ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE, cilt.27, sa.11, ss.1567-1572, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 27 Sayı: 11
  • Basım Tarihi: 2018
  • Doi Numarası: 10.17219/acem/74653
  • Dergi Adı: ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1567-1572
  • Anahtar Kelimeler: oxidative stress, carbonic anhydrases, hypoxia, HELLP syndrome, CARBONIC-ANHYDRASE-IX, MARKERS
  • Recep Tayyip Erdoğan Üniversitesi Adresli: Evet

Özet

Background. The HELLP syndrome (Hemolysis, Elevated Liver enzymes and Low Platelets) is a complication of severe pre-eclampsia, a condition characterized by oxidative stress elevation caused by disequilibrium between lipid peroxidation and antioxidant defense mechanisms, which, in turn, results in endothelial compromise and free radical-mediated cell damage. While several studies have examined the relationship between pre-eclampsia and oxidative stress, research investigating oxidative and hypoxic status in HELLP syndrome is limited.