Evaluation of carbapenem resistance using phenotypic and genotypic techniques in Enterobacteriaceae isolates

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Sahin K., Tekın A., Ozdas S., Akin D., Yapislar H., Dilek A. R., ...More

ANNALS OF CLINICAL MICROBIOLOGY AND ANTIMICROBIALS, vol.14, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 14
  • Publication Date: 2015
  • Doi Number: 10.1186/s12941-015-0105-1
  • Journal Name: ANNALS OF CLINICAL MICROBIOLOGY AND ANTIMICROBIALS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Keywords: Enterobacteriaceae, Carbapenemase, Carbapenem resistance, OXA-48, NDM-1, Modified Hodge test, Metallo-beta-lactamase antimicrobial gradient test, KLEBSIELLA-PNEUMONIAE, OXA-48, PLASMID, OXACILLINASE, EPIDEMIOLOGY, SURVEILLANCE, INFECTIONS, STRAIN, SPREAD, NDM-1
  • Recep Tayyip Erdoğan University Affiliated: Yes

Abstract

Background: Bacterial resistance to antibiotics is increasing worldwide. Antibiotic-resistant strains can lead to serious problems regarding treatment of infection. Carbapenem antibiotics are the final treatment option for infections caused by serious and life-threatening multidrug-resistant gram-negative bacteria. Therefore, an understanding of carbapenem resistance is important for infection control. In the study described herein, the phenotypic and genotypic features of carbapenem-resistant Enterobacteriaceae strains isolated in our hospital were evaluated.