Epidemiological and clinical characteristics and management of oropharyngeal tularemia outbreak


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UZUN M. O. , Yanik K., ERDEM M., Kostakoglu U. , YILMAZ G., Tanriverdi Cayci Y.

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.45, ss.902-906, 2015 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 45 Konu: 4
  • Basım Tarihi: 2015
  • Doi Numarası: 10.3906/sag-1403-111
  • Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Sayfa Sayıları: ss.902-906

Özet

Background/aim: The purpose of this study was to determine the epidemiological and clinical characteristics of patients diagnosed with tularemia and the effectiveness of the administered treatments.

Background/aim: The purpose of this study was to determine the epidemiological and clinical characteristics of patients diagnosed
with tularemia and the effectiveness of the administered treatments.
Materials and methods: Patients treated in our hospital between January 2009 and March 2011 and diagnosed with tularemia were
evaluated retrospectively. Patients’ epidemiological and clinical characteristics, administered treatments, and posttreatment findings
were recorded on patient monitoring forms.
Results: At anamnesis, 29% of patients used water from wells and 71% used water from the network supply; moreover, 48.4% had a
history of contact with animals and 87.1% a history of lethargy. At physical examination, 96.8% had a mass in the neck and 90.3% had
fever. Gentamycin + doxycycline therapy was administered to 45.2% of patients, while levofloxacin, gentamycin, and streptomycin
were used for the other patients. After treatment, neck masses persisted in 48.4% of patients and complaints of lethargy and fever in
6.5%. Treatment of these patients was initiated once tularemia had been diagnosed, as test results were announced about 3 weeks later.
Lymphadenopathy excision was performed on 19.4% of patients in whom neck mass persisted.
Conclusion: Appropriate empiric antibiotherapy should be commenced in patients presenting with neck mass, fever, and lethargy in
regions with tularemia epidemics.
Key words: Francisella tularensis, tularemia, epidemic