The Role of Hematological Inflammatory Biomarkers in the Diagnosis of Lung Cancer and in Predicting TNM Stage

GÖKSEL S., ÖZÇELİK N., Telatar G., ARDIÇ C.

CANCER INVESTIGATION, vol.39, no.6-7, pp.514-520, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 39 Issue: 6-7
  • Publication Date: 2021
  • Doi Number: 10.1080/07357907.2021.1938110
  • Journal Name: CANCER INVESTIGATION
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Veterinary Science Database
  • Page Numbers: pp.514-520
  • Keywords: Diagnostic value, lung cancer, mean platelet volume, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, NEUTROPHIL-TO-LYMPHOCYTE, PLATELET, RATIO
  • Recep Tayyip Erdoğan University Affiliated: Yes

Abstract

Objective The aim of study is to investigate whether hematological inflammatory biomarkers could be useful to detect patients with lung cancer. Methods The contribution of hematological biomarkers to the diagnosis of lung cancer and prediction of TNM was examined. Results NLR, PLR, MPV values were found to be higher in patients with lung cancer (all p < .001). NLR and PLR were found to be high, MPV was found to be lower in disease of advanced stage (p < .001). Conclusions This study found that NLR, PLR and MPV values were significantly higher in patients with lung cancer.