Design, synthesis, and characterization of some new benzimidazole derivatives and biological evaluation


BEKTAŞ H., Sokmen B. B. , AYDIN S., Mentese E. , Bektas A., Dilekci G.

JOURNAL OF HETEROCYCLIC CHEMISTRY, cilt.57, ss.2234-2242, 2020 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 57 Konu: 5
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1002/jhet.3943
  • Dergi Adı: JOURNAL OF HETEROCYCLIC CHEMISTRY
  • Sayfa Sayıları: ss.2234-2242

Özet

A new series of benzimidazole derivatives (1-15) containing 1,2,4-triazole, 1,3,4-thiadiazole, 1,3,4-oxadiazole, and thiazolidinon rings have been synthesized. All new synthesized benzimidazole compounds were confirmed by H-1 NMR, C-13 NMR spectra, and LC-MS, and they were examined for their antioxidant and antimicrobial activities. Compounds 7 and 1 showed the highest and the lowest antioxidant activities, respectively. The lowest minimum inhibition concentration value found in compound 5 against Enterobacter aerogenes.