Pleiotropic effects of HDL subfractions and HDL-associated enzymes on protection against coronary artery disease


Bostan M., Uydu H. A. , YILDIRMIŞ S., MALKOÇ M., Atak M. , Demir A., ...More

ACTA CARDIOLOGICA, vol.70, no.3, pp.333-340, 2015 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 70 Issue: 3
  • Publication Date: 2015
  • Doi Number: 10.1080/ac.70.3.3080638
  • Title of Journal : ACTA CARDIOLOGICA
  • Page Numbers: pp.333-340
  • Keywords: Atherosclerosis, high-density lipoprotein subfraction, lipoprotein-associated phospholipase A2, paraoxonase, DENSITY-LIPOPROTEIN, PHOSPHOLIPASE A(2), PARTICLE-SIZE, CARDIOVASCULAR-DISEASE, PARAOXONASE ACTIVITY, HEART-DISEASE, ATHEROSCLEROSIS, SUBCLASSES, RISK, MYELOPEROXIDASE

Abstract

Objective High-density lipoprotein cholesterol (HDL-C) levels are inversely related to the risk of coronary artery disease (CAD). Alterations in HDL-C subclass distribution and HDL-associated enzyme activities may be more important than total HDL levels for the progression of CAD. We intended to investigate the relationship of HDL-C subclass distribution and HDL-associated enzyme activities with CAD.