The Effect of Intratumoral Budding and Other Histological Features in Predicting Treatment Response in Breast Cancer Patients Receiving Neoadjuvant Therapy

Öztürk Ç., Öztürk S. D., Okcu O., Şen B., Yasin A. İ., Bedir R.

ISTANBUL MEDICAL JOURNAL, vol.23, no.4, pp.241-246, 2022 (ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 23 Issue: 4
  • Publication Date: 2022
  • Doi Number: 10.4274/imj.galenos.2022.69741
  • Journal Indexes: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Page Numbers: pp.241-246
  • Keywords: Intratumoral budding, neoadjuvant chemotherapy, treatment response, breast cancer, core biopsy, CHEMOTHERAPY, KI-67, PROGNOSIS, SURVIVAL
  • Recep Tayyip Erdoğan University Affiliated: Yes


Introduction: Neoadjuvant chemotherapy (NAC) is used with increasing frequency in breast cancers. Various clinicopathological parameters predict treatment response (TR). Tumor budding (TB), which is a prognostic parameter in many cancers, can be considered the first stage of the metastatic process. In our study, the relationship between TR and clinicopathological parameters and TB in core biopsy samples of patients before NAC was investigated.