Intensive Care Management of a Case of Cardiac Arrest Following Ketiapine Use
JOURNAL OF THE TURKISH SOCIETY OF INTENSIVE CARE-TURK YOGUN BAKM DERNEGI DERGISI, vol.10, no.3, pp.131-133, 2012 (ESCI)
- Publication Type: Article / Article
- Volume: 10 Issue: 3
- Publication Date: 2012
- Doi Number: 10.4274/tybdd.195
- Journal Name: JOURNAL OF THE TURKISH SOCIETY OF INTENSIVE CARE-TURK YOGUN BAKM DERNEGI DERGISI
- Journal Indexes: Emerging Sources Citation Index (ESCI)
- Page Numbers: pp.131-133
- Keywords: Quetiapine, cardiac arrest, coma, QUETIAPINE, OVERDOSE
- Open Archive Collection: AVESIS Open Access Collection
- Recep Tayyip Erdoğan University Affiliated: Yes
Abstract
Quetiapine is an antipsychotic commonly used in treatment of depression, bipolar disorders and schizophrenia. Quetiapine interacts with several receptors present in the central nervous system and therefore may cause diverse side effects like somnolence, coma or hyperglycemia. By prolonging QT interval, quetiapine may predispose the patient to tachycardia and other cardiac dysrhythmias and even cardiac arrest. Due to its antagonism on histaminergic receptors, quetiapine may cause respiratory depression and coma, necessitating mechanical ventilation support. On this paper, we discussed the management of an 80 year old male who is suspected to present with coma following quetiapine administration.