Protective effects of hyperbaric oxygen and iloprost on ischemia/reperfusion-induced lung injury in a rabbit model

Bozok S., Ilhan G., YILMAZ Y., DOKUMCU Z., Tumkaya L., KARAMUSTAFA H., ...Daha Fazla

EUROPEAN JOURNAL OF MEDICAL RESEARCH, cilt.17, 2012 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 17
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1186/2047-783x-17-14
  • Dergi Adı: EUROPEAN JOURNAL OF MEDICAL RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: Hyperbaric oxygen, Iloprost, Ischemia-reperfusion, Lung, Rabbit, INTESTINAL ISCHEMIA-REPERFUSION, LOWER TORSO ISCHEMIA, SKELETAL-MUSCLE, NEUTROPHIL SEQUESTRATION, SPINAL-CORD, TNF-ALPHA, RATS, PERMEABILITY, INHIBITION, ACTIVATION
  • Recep Tayyip Erdoğan Üniversitesi Adresli: Evet

Özet

Background: The role of multiorgan damage in the mortality caused by ischemic limb injury is still not clarified. The objective of this study was to examine the potential protective effects of hyperbaric oxygen (HBO) and iloprost (IL) therapy on lung damage induced by limb ischemia/reperfusion injury in a rabbit model, using both biochemical and histopathological aspects.