Loquat (Eriobotrya japonica L.) grown well for commercial purposes in subtropical regions nearly 30 countries and originated from China. The most important loquat producers in the world are China, Spain, Turkey, Pakistan, India, Italy and Brazil. In this study, ten pre-selected promising loquat genotypes sampled from eastern Black region and analyzed for their important morphological, biochemical and antioxidant characteristics. The standard cultivar ‘Sayda’ is also included in the study. The results indicated differences for all of the morphological, biochemical and antioxidant characteristics among tested genotypes. Fruit mass and fruit flesh percentage of the genotypes ranged from 35.40 g (LOQ-8) to 46.90 g (LOQ-5) and from 79.40 (%) to 86.32 (%) indicating some local genotypes had higher fruit mass and fruit flesh percentage than standard cultivar ‘Sayda’. Total phenolic content was the highest as 263 μg GAE/g in LOQ-7 genotype while the lowest in LOQ-8 genotype (185 μg GAE/g). LOQ-7 genotype had the highest total antioxidant capacity. Local genotypes in general have higher total phenolic, total carotenoid, vitamin C and antioxidant activity than cv. ‘Sayda’.