Determination of Exogenous Adrenaline Levels in Patients Undergoing Cardiopulmonary Resuscitation
ACS OMEGA, cilt.8, sa.22, ss.19425-19432, 2023 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 8 Sayı: 22
- Basım Tarihi: 2023
- Doi Numarası: 10.1021/acsomega.3c00555
- Dergi Adı: ACS OMEGA
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Directory of Open Access Journals
- Sayfa Sayıları: ss.19425-19432
- Recep Tayyip Erdoğan Üniversitesi Adresli: Evet
Özet
Core−shell quantum dot ZnS/CdSe screen-printed electrodes were used to
electrochemically measure human blood plasma levels of exogenous adrenaline
administered to cardiac arrest patients. The electrochemical behavior of adrenaline on
the modified electrode surface was investigated using differential pulse voltammetry
(DPV), cyclic voltammetry, and electrochemical impedance spectroscopy (EIS). Under
optimal conditions, the linear working ranges of the modified electrode were 0.001−3 μM
(DPV) and 0.001−300 μM (EIS). The best limit of detection for this concentration range
was 2.79 × 10−8 μM (DPV). The modified electrodes showed good reproducibility,
stability, and sensitivity and successfully detected adrenaline levels.