Is adalimumab protective in ischemia-reperfusion injury in lung?


Kurt A., TUMKAYA L. , Kalkan Y., TÜRÜT H. , CURE M. C. , CURE E., ...Daha Fazla

IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, cilt.18, ss.1093-1099, 2015 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 18 Konu: 11
  • Basım Tarihi: 2015
  • Dergi Adı: IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES
  • Sayfa Sayıları: ss.1093-1099

Özet

Objective(s): Increasing cytokines and reactive oxygen species (ROS) during ischemia reperfusion (I-R) leads to the lung damage. Adalimumab (Ada) is a potent tumor necrosis factor-alpha (TNF-alpha) inhibitor agent. We aimed to evaluate whether Ada would prevent the lung tissue from damage development over the I-R process.