Effects of iloprost and pentoxifylline on renal ischemia-reperfusion in rabbit model

EMRECAN B., TULUKOGLU E., Bozok S., KESTELLI M., ONEM G., Kuepelioglu A., ...Daha Fazla

EUROPEAN JOURNAL OF MEDICAL RESEARCH, cilt.11, sa.7, ss.295-299, 2006 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 11 Sayı: 7
  • Basım Tarihi: 2006
  • Dergi Adı: EUROPEAN JOURNAL OF MEDICAL RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.295-299
  • Recep Tayyip Erdoğan Üniversitesi Adresli: Hayır

Özet

Objective: In ischemia-reperfusion, Iloprost decreases neutrophil activation and aggregation besides inhibition of oxygen-free radical production. Pentoxifylline (Ptx) attenuates reperfusion-associated membrane injury and tissue edema, suppresses leukocyte adhesion and improves hindlimb blood flow during the reperfusion period. The primary hypothesis in this study was that Iloprost could present better protection than pentoxyfillin on renal ischemia-reperfusion in rabbit model.