Loss of function of folylpolyglutamate synthetase 1 reduces lignin content and improves cell wall digestibility in Arabidopsis


SRIVASTAVA A. C. , CHEN F., RAY T., PATTATHIL S., PENA M. J. , Avci U. , ...Daha Fazla

BIOTECHNOLOGY FOR BIOFUELS, cilt.8, 2015 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 8
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1186/s13068-015-0403-z
  • Dergi Adı: BIOTECHNOLOGY FOR BIOFUELS

Özet

Background: One-carbon (C1) metabolism is important for synthesizing a range of biologically important compounds that are essential for life. In plants, the C1 pathway is crucial for the synthesis of a large number of secondary metabolites, including lignin. Tetrahydrofolate and its derivatives, collectively referred to as folates, are crucial co-factors for C1 metabolic pathway enzymes. Given the link between the C1 and phenylpropanoid pathways, we evaluated whether folylpolyglutamate synthetase (FPGS), an enzyme that catalyzes the addition of a glutamate tail to folates to form folylpolyglutamates, can be a viable target for reducing cell wall recalcitrance in plants.