The LDL/HDL ratio and atherosclerosis in ankylosing spondylitis

Kucuk, A.; Uslu, A.; Icli, A.; Cure, E.; Arslan, S.; Turkmen, K.; Toker, A.; Kayrak, M.

doi:10.1007/s00393-016-0092-4

The LDL/HDL ratio and atherosclerosis in ankylosing spondylitis

Kucuk A., Uslu A. U., Icli A., Cure E., Arslan S., Turkmen K., ...Daha Fazla

ZEITSCHRIFT FUR RHEUMATOLOGIE, cilt.76, sa.1, ss.58-63, 2017 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 76 Sayı: 1
Basım Tarihi: 2017
Doi Numarası: 10.1007/s00393-016-0092-4
Dergi Adı: ZEITSCHRIFT FUR RHEUMATOLOGIE
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.58-63
Recep Tayyip Erdoğan Üniversitesi Adresli: Hayır

Özet

In ankylosing spondylitis (AS) patients, cardiac and vascular involvement may manifest as atherosclerosis and coronary artery disease. Systemic inflammation, oxidative stress, increased low-density lipoprotein (LDL) cholesterol and decreased high-density lipoprotein (HDL) cholesterol constitute a significant risk for atherosclerosis. This study investigated the relationship between carotid intima-media thickness (CIMT), LDL/HDL ratio, total oxidant status (TOS; an indicator of oxidative stress) and ischemic modified albumin (IMA; an ischemic marker in AS patients).