The LDL/HDL ratio and atherosclerosis in ankylosing spondylitis

Kucuk A., Uslu A. U., Icli A., Cure E., Arslan S., Turkmen K., ...More

ZEITSCHRIFT FUR RHEUMATOLOGIE, vol.76, no.1, pp.58-63, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 76 Issue: 1
  • Publication Date: 2017
  • Doi Number: 10.1007/s00393-016-0092-4
  • Journal Name: ZEITSCHRIFT FUR RHEUMATOLOGIE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.58-63
  • Recep Tayyip Erdoğan University Affiliated: No

Abstract

In ankylosing spondylitis (AS) patients, cardiac and vascular involvement may manifest as atherosclerosis and coronary artery disease. Systemic inflammation, oxidative stress, increased low-density lipoprotein (LDL) cholesterol and decreased high-density lipoprotein (HDL) cholesterol constitute a significant risk for atherosclerosis. This study investigated the relationship between carotid intima-media thickness (CIMT), LDL/HDL ratio, total oxidant status (TOS; an indicator of oxidative stress) and ischemic modified albumin (IMA; an ischemic marker in AS patients).