The LDL/HDL ratio and atherosclerosis in ankylosing spondylitis

Kucuk A., Uslu A. U., Icli A., Cure E., Arslan S., Turkmen K., ...Daha Fazla

ZEITSCHRIFT FUR RHEUMATOLOGIE, cilt.76, sa.1, ss.58-63, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 76 Sayı: 1
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1007/s00393-016-0092-4
  • Dergi Adı: ZEITSCHRIFT FUR RHEUMATOLOGIE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.58-63
  • Recep Tayyip Erdoğan Üniversitesi Adresli: Hayır

Özet

In ankylosing spondylitis (AS) patients, cardiac and vascular involvement may manifest as atherosclerosis and coronary artery disease. Systemic inflammation, oxidative stress, increased low-density lipoprotein (LDL) cholesterol and decreased high-density lipoprotein (HDL) cholesterol constitute a significant risk for atherosclerosis. This study investigated the relationship between carotid intima-media thickness (CIMT), LDL/HDL ratio, total oxidant status (TOS; an indicator of oxidative stress) and ischemic modified albumin (IMA; an ischemic marker in AS patients).