Akademik Veri Yönetim Sistemi
JOURNAL OF PERSONALIZED MEDICINE, cilt.14, sa.3, ss.247-257, 2024 (SCI-Expanded)
The study aimed to assess the pleth variability index (PVI) in patients undergoing lumbar
disc herniation surgery under general and spinal anesthesia, exploring its correlation with fluid
responsiveness, position, and hemodynamic parameters. Methods: This prospective study included
88 ASA 1–2 patients, aged 18–65, undergoing 1–3 h elective lumbar disc herniation surgery. Patients
in groups GA and SA were observed for demographic, operative, and hemodynamic parameters
at specified time points. (3) Results: PVI values were comparable between the GA and SA groups.
After 250 mL of fluid loading, both groups showed a significant decrease in basal PVI at T2. Prone
positions in GA exhibited higher PI values than in SA. The transition from a prone to supine position
maintained PVI, while pulse and MAP decreased.; (4) Conclusions: PVI values were comparable in
elective lumbar disc herniation surgery with general and spinal anesthesia. Both groups exhibited
significant a PVI decrease at T2 after 250 mL of fluid loading, indicating fluid responsiveness. In
general anesthesia, the prone position showed a lower MAP and higher PI values compared to spinal
anesthesia. PVI and PI, sensitive to general anesthesia changes, could have beneficial additions to
standard hemodynamic monitoring in spinal anesthesia management.
Keywords: pleth variability index; general anesthesia; spinal anesthesia; perfusion index; prone
position; lumbar disc hernia surgery