No apparent correlation between Behcet's disease and oxidative stress disturbance

SAGLAM H., KAYA E., Cemek M., Cicek Y., Kulac M., Karaca S.

CLINICAL HEMORHEOLOGY AND MICROCIRCULATION, vol.44, no.4, pp.287-296, 2010 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 44 Issue: 4
  • Publication Date: 2010
  • Doi Number: 10.3233/ch-2010-1278
  • Journal Name: CLINICAL HEMORHEOLOGY AND MICROCIRCULATION
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.287-296
  • Recep Tayyip Erdoğan University Affiliated: Yes

Abstract

Behcet's disease (BD) is a chronic, progressive and inflammatory multisystemic disease, that significantly affects the cardiovascular system. Oxidative stress (OS) is a disturbance in oxidant/antioxidant balance in favor of oxidants. The OS that increases acutely and chronically due to the inflammatory process plays an important role in the pathogenesis of the cardiovascular system effects of the disease by causing endothelial dysfunction in vascular structures. The aim of our study was to investigate the relationship between OS and myocardial perfusion, which is based on microvascular dysfunction, in BD.