Serum pigment epithelium-derived factor levels are increased in patients with biopsy-proven nonalcoholic fatty liver disease and independently associated with liver steatosis

YILMAZ Y., EREN F., Ayyildiz T., Colak Y., Kurt R., Senates E., ...More

CLINICA CHIMICA ACTA, vol.412, pp.2296-2299, 2011 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 412
  • Publication Date: 2011
  • Doi Number: 10.1016/j.cca.2011.08.025
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.2296-2299
  • Keywords: Pigment epithelium-derived factor, Nonalcoholic fatty liver disease, Enzyme-linked immunosorbent assay, Steatosis, ENDOTHELIAL GROWTH-FACTOR, FACTOR PEDF, METABOLIC SYNDROME, INSULIN-RESISTANCE, ANGIOGENESIS, ACTIVATION, CELLS
  • Recep Tayyip Erdoğan University Affiliated: No


Background: Increased serum concentrations of pigment epithelium-derived factor (PEDF) have been linked to the metabolic syndrome in the general population. However, the relationship between serum PEDF and nonalcoholic fatty liver disease (NAFLD), a hepatic manifestation of the metabolic syndrome, remains unknown.