Serum pigment epithelium-derived factor levels are increased in patients with biopsy-proven nonalcoholic fatty liver disease and independently associated with liver steatosis

YILMAZ, YUSUF; EREN, FATİH; Ayyildiz, Talat; Colak, Yasar; Kurt, Ramazan; Senates, Ebubekir; Tuncer, Ilyas; Dolar, Enver; Imeryuz, Nese

doi:10.1016/j.cca.2011.08.025

Serum pigment epithelium-derived factor levels are increased in patients with biopsy-proven nonalcoholic fatty liver disease and independently associated with liver steatosis

YILMAZ Y., EREN F., Ayyildiz T., Colak Y., Kurt R., Senates E., ...Daha Fazla

CLINICA CHIMICA ACTA, cilt.412, ss.2296-2299, 2011 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 412
Basım Tarihi: 2011
Doi Numarası: 10.1016/j.cca.2011.08.025
Dergi Adı: CLINICA CHIMICA ACTA
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.2296-2299
Anahtar Kelimeler: Pigment epithelium-derived factor, Nonalcoholic fatty liver disease, Enzyme-linked immunosorbent assay, Steatosis, ENDOTHELIAL GROWTH-FACTOR, FACTOR PEDF, METABOLIC SYNDROME, INSULIN-RESISTANCE, ANGIOGENESIS, ACTIVATION, CELLS
Recep Tayyip Erdoğan Üniversitesi Adresli: Hayır

Özet

Background: Increased serum concentrations of pigment epithelium-derived factor (PEDF) have been linked to the metabolic syndrome in the general population. However, the relationship between serum PEDF and nonalcoholic fatty liver disease (NAFLD), a hepatic manifestation of the metabolic syndrome, remains unknown.