Letter to the Editor: <i>GEN1</i> as a potential therapeutic target in gastric cancer
WORLD JOURNAL OF GASTROINTESTINAL ONCOLOGY, cilt.18, sa.9, 2026 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Kısa Makale
- Cilt numarası: 18 Sayı: 9
- Basım Tarihi: 2026
- Doi Numarası: 10.4251/wjgo.v18.i9.116896
- Dergi Adı: WORLD JOURNAL OF GASTROINTESTINAL ONCOLOGY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Recep Tayyip Erdoğan Üniversitesi Adresli: Evet
Özet
I thoroughly reviewed the paper by Zhang et al published in the recent issue of World Journal of Gastrointestinal Oncology, and commend the authors for their in-depth analysis of the oncogenic functions of GEN1 in gastric cancer (GC). The recent work by Zhang et al sheds light on the oncogenic role of GEN1 in GC, which is involved in cell cycle progression, mitochondrial function, ferroptosis, and chemotherapeutic sensitivity. The findings of this study are of scientific interest and future studies to increase the translational relevance of the work are proposed.