Emergency coronary bypass surgery in patients under the influence of dual antiplatelet therapy: effects of tranexamic acid and desmopressin acetate

ALTUN G., Hemsinli D., PULATHAN Z., Civelek A.

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.47, sa.6, ss.1708-1714, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 47 Sayı: 6
  • Basım Tarihi: 2017
  • Doi Numarası: 10.3906/sag-1612-140
  • Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.1708-1714
  • Anahtar Kelimeler: Clopidogrel, coronary bypass surgery, desmopressin acetate, dual antiplatelet therapy, tranexamic acid, CARDIOPULMONARY BYPASS, DOUBLE-BLIND, BLOOD-LOSS, CLOPIDOGREL, TRANSFUSIONS, ASPIRIN
  • Recep Tayyip Erdoğan Üniversitesi Adresli: Hayır

Özet

Background/aim: Bleeding in patients undergoing coronary artery bypass grafting (CABG) while using dual antiplatelet therapy (DAPT) is a cause of significant morbidity and mortality. The aim of this study is to examine the perioperative hemostatic effects of tranexamic acid (TnX-A) and desmopressin acetate (Des) in these patients.