PD-1 and PD-L2 expression predict relapse risk and poor survival in patients with stage III colorectal cancer


Zengin M., Zergeroglu S., Okcu O., Benek S.

CELLULAR ONCOLOGY, vol.44, no.2, pp.423-432, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 44 Issue: 2
  • Publication Date: 2021
  • Doi Number: 10.1007/s13402-020-00579-5
  • Journal Name: CELLULAR ONCOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, Biotechnology Research Abstracts, EMBASE, MEDLINE
  • Page Numbers: pp.423-432
  • Keywords: Colorectal cancer, PD-1, PDL-2, Prognostic biomarkers, Stage III
  • Recep Tayyip Erdoğan University Affiliated: Yes

Abstract

Background Immune responses have long been an area of interest in cancer research. In this study, the effects of programmed cell death-1 (PD-1) and its ligand (PD-L2) on the prognosis of colorectal cancer (CRC) were investigated.