Efficient Synthesis of Benzimidazoles Containing 1,2,4-Triazol-3-One Nucleus Using Microwave Technique


Mentese E. , KAHVECİ B.

CHEMISTRY OF HETEROCYCLIC COMPOUNDS, vol.52, no.11, pp.948-951, 2016 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 52 Issue: 11
  • Publication Date: 2016
  • Doi Number: 10.1007/s10593-017-1991-2
  • Title of Journal : CHEMISTRY OF HETEROCYCLIC COMPOUNDS
  • Page Numbers: pp.948-951

Abstract

A series of new compounds containing both benzimidazole and 1,2,4-triazol-3-one rings was synthesized by microwave irradiation of mixtures containing 5-(alkyl/phenyl)-4-(4-carboxyphenyl)-2,4-dihydro-3H-1,2,4-triazol-3-ones and 1,2-diaminobenzene derivatives. Also, benzimidazole derivatives were synthesized by the reaction of ethyl 2-(ethoxy(alkyl/phenyl)methylene)hydrazine-1-carboxylates with 2-aminobenzimidazole. A rapid and efficient combination of 1,2,4-triazol-3-one and benzimidazole ring systems was achieved for the first time in this study.