Efficient Synthesis of Benzimidazoles Containing 1,2,4-Triazol-3-One Nucleus Using Microwave Technique
CHEMISTRY OF HETEROCYCLIC COMPOUNDS, cilt.52, sa.11, ss.948-951, 2016 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 52 Sayı: 11
- Basım Tarihi: 2016
- Doi Numarası: 10.1007/s10593-017-1991-2
- Dergi Adı: CHEMISTRY OF HETEROCYCLIC COMPOUNDS
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.948-951
- Anahtar Kelimeler: 2-aminobenzimidazole, benzimidazole, hydrazone, 1,2,4-triazol-3-one, microwave synthesis, ASSISTED SYNTHESIS, DERIVATIVES
- Recep Tayyip Erdoğan Üniversitesi Adresli: Evet
Özet
A series of new compounds containing both benzimidazole and 1,2,4-triazol-3-one rings was synthesized by microwave irradiation of mixtures containing 5-(alkyl/phenyl)-4-(4-carboxyphenyl)-2,4-dihydro-3H-1,2,4-triazol-3-ones and 1,2-diaminobenzene derivatives. Also, benzimidazole derivatives were synthesized by the reaction of ethyl 2-(ethoxy(alkyl/phenyl)methylene)hydrazine-1-carboxylates with 2-aminobenzimidazole. A rapid and efficient combination of 1,2,4-triazol-3-one and benzimidazole ring systems was achieved for the first time in this study.