Investigation of the effectiveness of algan hemostatic agent in bleeding control using an experimental partial splenectomy model in rats

Midi A., EKİCİ H., KUMANDAŞ A., Durmus O., Bodic B., Tiryaki M., ...More

MARMARA MEDICAL JOURNAL, vol.32, no.1, pp.27-32, 2019 (ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 32 Issue: 1
  • Publication Date: 2019
  • Doi Number: 10.5472/marumj.518821
  • Journal Name: MARMARA MEDICAL JOURNAL
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.27-32
  • Keywords: Algan hemostatic agent, Hemostasis, Rat, Bleeding control, Splenectomy, MEDICINAL-PLANT EXTRACT, ANKAFERD BLOOD STOPPER, N-ACETYL GLUCOSAMINE, FIBRIN SEALANT, POSTOPERATIVE ADHESIONS, ACHIEVING HEMOSTASIS, SPLENIC INJURY, SWINE MODEL, EFFICACY, MANAGEMENT
  • Recep Tayyip Erdoğan University Affiliated: Yes

Abstract

Objective: Algan hemostatic agent (AHA) is a plant-based hemostatic agent produced in Turkey. Although, there is a great improvement in the hemostatic technologies, more effective hemostatic products are required to be produced. The aim of this study was to demonstrate the efficacy of AHA in a partial splenectomy model in rats. In addition, in this model, postoperative abdominal adhesion was evaluated.