JOURNAL OF CANCER RESEARCH AND THERAPEUTICS, cilt.11, sa.1, ss.164-169, 2015 (SCI-Expanded)
Aims: Although methotrexate (mtx) is a widely used agent to treat cancer and inflammatory diseases, its hepatotoxic effect limits for clinical utility. We aimed to investigate whether infliximab (inf), an inhibitor of tumor necrosis factor-alpha (TNF-alpha) has a protective effect against mtx-induced hepatotoxicity.