Synchronous Primary Carcinoma in 5 Different Organs of a Female Genital Tract An Unusual Case and Review of the Literature

Atasever M., Yilmaz B., Dilek G., Akcay E. Y., Kelekci S.

INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, vol.19, no.4, pp.802-807, 2009 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 19 Issue: 4
  • Publication Date: 2009
  • Doi Number: 10.1111/igc.0b013e3181a39b95
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.802-807
  • Keywords: Gynecologic malignancies, Synchronous primary tumors, Ovarian cancer, Fallopian tube cancer, Endometrial cancer, Cervical cancer, PRIMARY NEOPLASMS, UTERINE CORPUS, OVARY, ENDOMETRIUM, MALIGNANCIES, CANCERS, TUMORS
  • Recep Tayyip Erdoğan University Affiliated: No


The occurrence of double simultaneous primary cancers of the female reproductive tract is a common event. However, the occurrence of synchronous primary quadruple gynecologic malignancies is extremely rare. In this report, the clinical and pathological findings of a 35-year-old female patient with synchronous primary gynecologic cancers regarding papillary serous carcinoma of the left ovary, microinvasive carcinoma In situ of the left and right uterine tubes, endometrial intraepithelial carcinoma of the endometrium, and endocervical carcinoma in situ of the uterine cervix were presented. To our knowledge, the patient presented is the first case in aspect of accompanying ovarian papillary serous carcinoma to bilateral tubal microinvasive carcinoma in situ, endometrial intraepithelial carcinoma, and endocervical carcinoma in situ of the uterine cervix.