In this study, we have evaluated the effect of depuration on the bacterias, the mineral matters, the fatty acids and the amino acids in the carpet shells and the quality indexes in terms of human health. The carpet shells that underwent the depuration process for a total of 72 hours in a closed loop system were analyzed every 12 hours. There was a significant decrease in the total number of bacteria depending on the duration of depuration. E. coli, Salmonella spp., Staphylococcus aureus, Listeria monocyto genes,Vibrio parahaemolyticus and Vibrio cholera could not be determined in the carpet shells during depuration. 48-hour processing time was determined to be significant for a decline in Co, Fe, Al, Cu, and Mn levels due to depuration in the carpet shells. Zn, Cu, Ni and Cr levels were found to remain in the national and international limit values during the study. Al and Mn levels were envisaged to be appropriate for all the thresholds specified in terms of human health. The values of total essential amino acids (Sigma EAA) and non-essential amino acids (Sigma NEAA) at the end of depuration process were higher than their initial values and the EAA/NEAA ratio was determined between 0.82-1.09. It was found in the carpet shells during depuration that polyunsaturated fatty acids (PUFA) were between 57.64-58.88%, saturated fatty acids (SFA) were between 23.72-25.46% and monounsaturated fatty acids (MUFA) were between 8.51-9.75%. EPA, DHA and omega-3 levels which play an important role in human nutrition were found to be high. Moreover, the quality indexes of the fatty acid (AI, TI, FLQ, w6/w3, h/H) were determined to be at appropriate values for human health.